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BCL6 inhibitor 8c
CAS No. 2130878-25-8
BCL6 inhibitor 8c ( BCL6IN8c; BCL6 inhibitor 8c; BCL6 inhibitor-8c; BCL6 inhibitor8c )
Catalog No. M13392 CAS No. 2130878-25-8
A novel potent, in vivo-active BCL6 inhibitor with IC50 of 0.1 uM in ELISA assays.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 822 | Get Quote |
|
| 100MG | 1341 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameBCL6 inhibitor 8c
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NoteResearch use only, not for human use.
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Brief DescriptionA novel potent, in vivo-active BCL6 inhibitor with IC50 of 0.1 uM in ELISA assays.
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DescriptionA novel potent, in vivo-active BCL6 inhibitor with IC50 of 0.1 uM in ELISA assays; exhibits good cellular BCL6BTB/ BCoR PPI inhibitory activity in the submicromolar range (M2H IC50=0.72 uM), showed a good pharmacokinetic profile, which is acceptable for both in vitro and in vivo studies.
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SynonymsBCL6IN8c; BCL6 inhibitor 8c; BCL6 inhibitor-8c; BCL6 inhibitor8c
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PathwayAngiogenesis
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TargetBcl-2
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RecptorBcl-2
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Research Area——
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Indication——
Chemical Information
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CAS Number2130878-25-8
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Formula Weight417.85
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Molecular FormulaC20H20ClN3O5
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C1NC2=C(C=C(NC3=CC(OC4CCOCC4)=C([N+]([O-])=O)C=C3Cl)C=C2)CC1
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Chemical Name6-((2-Chloro-4-nitro-5-((tetrahydro-2H-pyran-4-yl)oxy)phenyl)amino)-3,4-dihydroquinolin-2(1H)-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Yasui T, et al. Bioorg Med Chem. 2017 Sep 1;25(17):4876-4886.
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